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當前位置：首頁產(chǎn)品中心重組蛋白Z03134IL-6, Human(CHO-expressed)

IL-6, Human(CHO-expressed)
產(chǎn)品簡介：

IL-6, Human(CHO-expressed)：Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that acts in both pro-inflammatory and anti-inflammatory responses. It is produced mainly

產(chǎn)品型號：Z03134

更新時間：2025-11-06

廠商性質(zhì)：代理商

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產(chǎn)品介紹

Interleukin-6 (IL-6), also known as BSF-2, CDF and IFNB2, is a pleiotropic cytokine that acts in both pro-inflammatory and anti-inflammatory responses. It is produced mainly by T cells, macrophages, monocytes, endothelial cells and muscle cells. IL-6 binds to IL-6 receptor (IL-6R) to trigger the association of IL-6R with gp130, inducing signal transduction through JAKs and STATs. The biological functions of IL-6 are diverse. It stimulates B cell differentiation and antibody production, myeloma and plasmacytoma growth, as well as nerve cell differentiation. It also acts as a myokine, produced by muscle cells in response to muscle contraction, to be released to the blood stream to help break down fats and improve insulin resistance.

產(chǎn)品簡介
SpeciesHuman
Protein Construction
IL-6 (Pro29-Met212)
Accession # Q75MH2
Purity> 95% as analyzed by SDS-PAGE
Endotoxin Level≤ 0.2 EU/μg of protein by gel clotting method
Biological ActivityED50 < 1.0 ng/ml, measured in a cell proliferation assay using TF-1 cells.
Expression SystemCHO
Apparent Molecular Weight15~25 kDa, on SDS-PAGE under reducing conditions.
FormulationLyophilized after extensive dialysis against PBS.
ReconstitutionIt is recommended that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute the lyophilized powder in ddH2O or PBS up to 100 μg/ml.
Storage & StabilityUpon receiving, this product remains stable for 6 months at lower than -70°C. Upon reconstitution, the product should be stable for 1 week at 4°C or for 3 months at -20°C. Avoid repeated freeze-thaw cycles.


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